WHO: 2 UK mpox cases first local transmissions in Europe

London — Two new cases of the mpox variant clade 1b detected in the U.K. are the first locally transmitted cases in Europe and the first outside Africa, the World Health Organization said Tuesday.

The U.K. Health Security Agency (UKHSA) confirmed late Monday that the two new cases were household contacts of Britain’s first case identified last week, bringing the country’s total confirmed cases to three.

The WHO warned that European states should be prepared for “rapid action” to contain the latest mpox variant, which spreads through close physical contact including sexual relations and sharing closed spaces.

The two cases are also the first to be locally transmitted outside Africa since August 2024, when the WHO declared the outbreak of the new variant an international public health emergency — its highest level of alarm.

Those affected are under specialist care and the risk to the U.K. population “remains low,” UKHSA said.

The original case was detected after the person traveled to several African countries on holiday and returned to the U.K. on Oct. 21.

The patient developed flu-like symptoms more than 24 hours later and, on Oct. 24, started to develop a rash that worsened in the following days.

Mpox, a viral disease related to smallpox, has two types, clade 1 and clade 2. Symptoms include fever, a skin rash or pus-filled blisters, swollen lymph nodes and body aches.

The WHO first declared an international public health emergency in 2022 over the spread of clade 2. That outbreak mostly affected gay and bisexual men in Europe and the United States.

Vaccination and awareness drives in many countries helped stem the number of worldwide cases and the WHO lifted the emergency in May 2023 after reporting 140 deaths out of around 87,400 cases.

In 2024, a two-pronged epidemic of clade 1 and clade 1b, a new strain that affects children, has spread widely in the Democratic Republic of Congo.

The new strain has also been recorded in neighboring Burundi, Kenya, Rwanda and Uganda, with imported cases in Sweden, India, Thailand, Germany and the U.K.

WHO identifies priority pathogens for new vaccines development

Geneva — The World Health Organization on Tuesday listed 17 pathogens that cause widespread disease and death, including HIV, malaria and tuberculosis, for which it said new vaccines were “urgently needed.”

The U.N. health agency said that it with its list was providing the first global effort to systematically prioritize endemic pathogens based on criteria including disease burdens, antimicrobial resistance risk and the socioeconomic impact.

“We need to do this because we would like to shift the focus from developing vaccines away from commercial returns towards regional and global health needs,” Mateusz Hasso-Agopsowicz, a WHO vaccine specialist, told reporters in Geneva via video link from Poland.

The study reconfirms longstanding priorities for vaccine research and development, including HIV, malaria and tuberculosis — three diseases that collectively kill nearly 2.5 million people each year, WHO said.

But it also identifies lesser-known pathogens as top disease control priorities, highlighting the urgency to develop new vaccines for pathogens that are becoming increasingly resistant to antimicrobials.

Among them was Group A streptococcus, which causes severe infections and contributes to some 280,000 deaths from rheumatic heart disease each year, mainly in lower-income countries.

Ita also highlights the dangers of Klebsiella pneumoniae — a bacterium that is responsible for around 40% of neonatal deaths due to blood infection, or sepsis, in low-income countries.

These vaccines “would not only significantly reduce diseases that greatly impact communities today but also reduce the medical costs that families and health systems face,” WHO vaccine chief Kate O’Brien said in a statement.

Vaccines for the various pathogens listed are at different stages of development, WHO said, with some like ones for HIV, Group A streptococcus and hepatitis C virus still at the research stage. 

Others, like ones for dengue and tuberculosis, have been developed and are approaching regulatory approval or introduction.

Hasso-Agopsowicz explained that the 17 listed pathogens were wreaking the most havoc in lower-income countries, explaining why more progress has not been made previously on developing vaccines against them.

“What typically has happened in the past is that vaccine research and development has been influenced by profitability of new vaccines. What that means is that diseases that severely affect low-income regions unfortunately receive much less attention,” he said.

With the new list, he said, “we want to change the focus… so that the new vaccine research and development is driven by health burden and not just commercial opportunities.”

WHO continues talks to prepare world for pandemics

geneva — World Health Organization member countries resumed negotiations Monday to finalize an agreement on pandemic prevention, with outbreaks of mpox, Marburg and H5N1 stressing the urgency of reaching an agreement without repeating the deadly mistakes of COVID-19.

After more than two years of negotiations, there is hope of reaching an agreement in the next 15 days, especially since the negotiators have agreed to postpone discussions on the most contentious points: the sharing of knowledge and equitable access to medical advances.

Recent negotiations at COP16 in Colombia on biodiversity, which provided for a comparable mechanism, stumbled on this point.

WHO chief Tedros Adhanom Ghebreyesus stressed the need to balance timeliness and workable deal.

“Time is not our friend,” Tedros told national negotiators at the opening of the talks. “COVID is still circulating. Mpox is a global health emergency. We have a Marburg outbreak and H5N1 spreading. The next pandemic will not wait.”

Never again

In December 2021, fearing a repeat of the catastrophe caused by COVID-19, which killed millions of people, the 194 member countries of WHO agreed to reach an agreement on pandemic prevention, preparedness and response.

The emergence of a new strain of mpox, the deadly Marburg virus outbreak in Rwanda and the spread of H5N1 avian flu in recent months have clarified the issues.

Diplomats have agreed on most of the draft’s 37 articles during 11 rounds of negotiations.

The main section on which consensus will need to be found concerns access to pathogens for the scientific community and medical research, and then to products to combat the pandemic such as vaccines or other tests derived from this research.

In order not to block everything, the idea is to postpone the discussion on the details of the pathogen access and benefit sharing system (PABS) until later.

Battle for fairness

For the moment, there is an impasse between rich and poor countries, which have not forgotten that they were abandoned to their fate during the COVID-19 pandemic.

“If the world has failed on one thing, it is on the issue of equity” during the COVID-19 pandemic, the head of WHO stressed on Friday.

“Africa was left behind at the time, and this should not happen,” Tedros said.

‘Bitter taste’

Helen Clark, former New Zealand Prime Minister, believes that “the South sees the North as protecting its pharmaceutical industries,” and this “has left an incredibly bitter taste between the North and the South.”

The International Federation of Pharmaceutical Manufacturers and Associations called for an agreement “allowing the private sector to innovate.”

“Intellectual property must be respected, and technology transfer must always be voluntary and on mutually agreed terms,” the federation insisted.

Among the country representatives, Malaysia, speaking on behalf of a group of developing countries known as the Equity Group, said “major improvements are still desperately needed in many areas.”

It demanded that at least 20% of real-time production of vaccines, tests and treatments go to developing countries.

Tanzania, on behalf of 48 African countries, said it could not “accept an agreement not based on equity.”

The Indonesian negotiator said an agreement that only preserves the status quo is unacceptable, because “empty promises will not save lives.”

China insisted that “quality should not be sacrificed for time.”

Germany’s representative called for an acceleration of the talks to “focus on what is achievable.”

Public funding for nature conservation stalls at COP16, eyes on private investment

CALI, Colombia — Wealthy nations appeared to hit a limit with how much they are willing to pay to conserve nature around the world, instead shifting their focus at the two-week U.N. biodiversity summit toward discussions of private money filling the funding gap.

At the COP16 negotiations in Cali, Colombia, countries failed to figure out how they would mobilize $200 billion annually in conservation funding by 2030, including $30 billion that would come directly from rich nations.

That money, pledged two years ago as part of the landmark Kunming-Montreal Global Biodiversity Framework agreement, is meant to finance activities that boost nature, such as sustainable farming or patrolling wildlife reserves.

But there was no consensus as talks dragged on beyond the summit’s scheduled end on Friday, during which dozens of delegations departed. By Saturday morning’s roll call, there was no longer a quorum among the nearly 200 nations for an agreement to pass, forcing organizers to abruptly suspend the meeting.

“I am both saddened and enraged by the non-outcome of COP16,” said Shilps Gautam, chief executive of project finance firm Opna.

“The wild thing about the nature financing discussions is that the numbers discussed are already a pittance.”

Human activities such as farming, mining, and urban development are increasingly pushing nature into crisis, with 1 million or so plant and animal species thought to be at risk of extinction.

Climate change, a result of fossil fuel burning, is also adding to nature’s woes by raising temperatures and disrupting weather cycles.

Countries will meet again in Azerbaijan next week for the U.N.’s COP29 climate summit, which again will be focused on the steep need for funding from wealthy nations to their poorer counterparts to help shoulder climate costs.

Little money from rich nations

Even before the talks broke down, developed nations had signaled an unwillingness to offer large amounts of cash.

European governments including Germany and the Netherlands have slashed their foreign aid budgets over the last year, while France and the U.K. are also cutting back.

Government development money specifically targeted at nature conservation abroad fell to $3.8 billion in 2022 compared with $4.6 billion in 2015, according to the Organization for Economic Co-operation and Development.

At COP16, U.N. Secretary General Antonio Guterres demanded that countries make significant new contributions to the Global Biodiversity Framework Fund.

The response was muted. Nations at COP16 pledged $163 million in contributions to the fund, bringing total contributions to roughly $400 million – far from a major contribution to the $30 billion target from nations by 2030.

The United States, which is not a party to U.N. Convention on Biological Diversity, has not contributed.

“The public money is already leveraged as much as we can,” Florika Fink-Hooijer, the European Union’s director general of environment, told reporters at the summit.

“We now have to look at other sources of funding.”

Private cash

When it came to going after private capital, delegates at the COP16 summit agreed to a plan to charge pharmaceutical and other companies for their use of genetic information in the research and development of new commercial products.

Pharmaceutical companies Pfizer, Merck, AstraZeneca and Land Sanofi did not respond to request for comment on the deal.

Experts estimate the plan could generate about $1 billion annually.

That still doesn’t cover the billions needed to halt the collapse of ecosystems, like the Amazon rainforest or coral reefs. The world will need to devise ways for enticing private investment in nature-friendly projects, said Marcos Neto, director of global policy at the U.N. Development Program.

Some tools include green bonds or debt-for-nature swaps, whereby countries refinance their debt at lower interest rates in order to spend the savings on conservation. The World Economic Forum estimates that debt-for-nature swaps could generate $100 billion in nature funding.

French families sue TikTok over alleged failure to remove harmful content

PARIS — Seven French families have filed a lawsuit against social media giant TikTok, accusing the platform of exposing their adolescent children to harmful content that led to two of them taking their own lives at 15, their lawyer said on Monday.

The lawsuit alleges TikTok’s algorithm exposed the seven teenagers to videos promoting suicide, self-harm and eating disorders, lawyer Laure Boutron-Marmion told broadcaster franceinfo.

The families are taking joint legal action in the Créteil judicial court. Boutron-Marmion said it was the first such grouped case in Europe.

“The parents want TikTok’s legal liability to be recognized in court,” she said, adding: “This is a commercial company offering a product to consumers who are, in addition, minors. They must, therefore, answer for the product’s shortcomings.”

TikTok, like other social media platforms, has long faced scrutiny over the policing of content on its app.

As with Meta’s Facebook and Instagram, it faces hundreds of lawsuits in the U.S. accusing them of enticing and addicting millions of children to their platforms, damaging their mental health.

TikTok could not immediately be reached for comment on the allegations.

The company has previously said it took issues that were linked to children’s mental health seriously. CEO Shou Zi Chew this year told U.S. lawmakers the company has invested in measures to protect young people who use the app.

US tech firms warn Vietnam’s planned law to hamper data centers, social media

HANOI, Vietnam — U.S. tech companies have warned Vietnam’s government that a draft law to tighten rules on data protection and limit data transfers abroad would hamper social media platforms and data center operators from growing their businesses in the country.

The Southeast Asian nation with a population of 100 million is one of the world’s largest markets for Facebook and other online platforms, and is aiming to exponentially increase its data center industry with foreign investment in coming years.

The draft law “will make it challenging for tech companies, social media platforms and data center operators to reach the customers that rely on them daily,” said Jason Oxman, who chairs the Information Technology Industry Council (ITI), a trade association representing big tech companies including Meta, Google and data centers operator Equinix.

The draft law, being discussed in parliament, is also designed to ease authorities’ access to information and was urged by the ministry of public security, Vietnamese and foreign officials said.

The ministry of public security and the information ministry did not respond to attempts to contact them via email and phone.

Vietnam’s parliament is discussing the law in its current month-long session and is scheduled to pass it on Nov. 30 “if eligible,” according to its program, which is subject to changes.

Existing Vietnamese regulations already limit cross-border transfers of data under some circumstances, but they are rarely enforced.

It is unclear how the new law, if adopted, would impact foreign investment in the country. Reuters reported in August that Google was considering setting up a large data center in southern Vietnam before the draft law was presented in parliament.

Research firm BMI had said Vietnam could become a major regional player in the data center industry as limits on foreign ownership are set to end next year.

Among the provisions of the draft law is prior authorization for the transfer overseas of “core data” and “important data,” which are currently vaguely defined.

“That will hinder foreign business operations,” Oxman told Reuters.

Tech companies and other firms favor cross-border data flows to cut costs and improve services, but multiple jurisdictions, including the European Union and China, have limited those transfers, saying that allows them to better protect privacy and sensitive information.

Under the draft law, companies will have to share data with Vietnam’s ruling Communist Party and state organizations in multiple, vaguely defined cases including for “fulfilling a specific task in the public interest.”

The U.S. tech industry has raised concerns with Vietnamese authorities over “the undue expansion of government access to data,” Oxman said.

The new law “would cause significant compliance challenges for most private sector companies,” said Adam Sitkoff, executive director of the American Chamber of Commerce in Hanoi, noting talks were underway to persuade authorities to “reconsider the rushed legislative process” for the law.

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Germany’s Scholz summons top ministers over rival plans to fix economy 

Berlin — German Chancellor Olaf Scholz will hold meetings with his top two ministers to try to find common ground after they put forward contradictory plans to fix the nation’s ailing economy, a government source told Reuters on Sunday.  

A document leaked by Christian Lindner’s finance ministry raised eyebrows in Berlin last week, with its push for tax cuts and fiscal discipline widely interpreted as a challenge to the multibillion-euro investment plan put forward by Economy Minister Robert Habeck just days earlier.  

The stand-off is the latest escalation in a row over economic and industrial policy between the FDP, the Greens and Scholz’s Social Democrats that has fueled speculation of the coalition’s potential collapse, less than a year before elections are due.  

But a government source told Reuters that Scholz and the ministers would hold several meetings in the coming days, saying that “now that everyone has submitted their paper, we have to see how they fit with each other.”  

A worsening business outlook in Europe’s largest economy has widened divisions in Scholz’s ideologically disparate coalition over policy measures to drive growth, protect industrial jobs, and reinforce Germany’s position as a global industrial hub.  

While Habeck wants the creation of a fund to stimulate investment and to get around Germany’s strict fiscal spending rules, Lindner advocates tax cuts to spur the economy and an immediate halt on all new regulation.  

SPD leader Lars Klingbeil signaled openness to discussing Lindner’s proposals in a local newspaper interview, but said that some of them were untenable for his party, which released its own economic plan earlier in October.  

“Giving more to the rich, letting employees work longer and sending them into retirement later – it will come as no surprise to anyone that we think this is the wrong approach,” Klingbeil told the Augsburger Allgemeine newspaper. 

Mpox cases in Congo may be stabilizing, but more vaccines needed to stamp out virus 

Goma, Congo — Some health officials say mpox cases in Congo appear to be “stabilizing” — a possible sign that the main epidemic for which the World Health Organization made a global emergency declaration in August might be on the decline.  

In recent weeks, Congo has reported about 200 to 300 lab-confirmed mpox cases every week, according to WHO. That’s down from nearly 400 cases a week in July. The decline is also apparent in Kamituga, the mining city in the eastern part of Congo where the new, more infectious variant of mpox first emerged.  

But the U.N. health agency acknowledged Friday that only 40% to 50% of suspected infections in Congo were being tested — and that the virus is continuing to spread in some parts of the country and elsewhere, including Uganda.  

While doctors are encouraged by the drop in infections in some parts of Congo, it’s still not clear what kinds of physical contact is driving the outbreak. Health experts are also frustrated by the low number of vaccine doses the central African nation has received — 265,000 — and say that delivering the vaccine to where it’s needed in the sprawling country is proving difficult. WHO estimates 50,000 people have been immunized in Congo, which has a population of 110 million.  

Scientists also say there needs to be an urgent, broader vaccination effort for the entire continent to halt mpox’s spread and avoid further worrisome genetic mutations, like the one detected earlier this year in Congo after months of low-level circulation.  

“If we miss this opportunity, the likelihood of another significant outbreak increases substantially,” said Dr. Zakary Rhissa, who heads operations in Congo for the charity Alima.  

So far this year, there have been roughly 43,000 suspected cases in Africa and more than 1,000 people have died, mostly in Congo.  

“We’ve seen how past outbreaks, such as the one in Nigeria in 2017, can lead to larger global events if not effectively contained,” he said. The 2017 epidemic ended up leading to the 2022 global outbreak of mpox that affected more than 100 countries.  

Rhissa said the decline in cases in Kamituga — where mpox initially spread among sex workers and miners — is an opening to put more programs in place for vaccination, surveillance and education.  

Georgette Hamuli, an 18-year-old sex worker, hadn’t been aware of mpox until immunization teams arrived last week in the poor neighborhood where she works in Goma, the biggest city in eastern Congo.  

“They told us we’re highly exposed to the risk of infection,” she said. “We insist on condoms with our clients, but some refuse … if they don’t want to use a condom, they double the amount they pay.”  

Hamuli said she and other friends who are sex workers each received 2,000 Congolese francs ($0.70) from a charity to get vaccinated against mpox — but it wasn’t the money that swayed her. 

“The vaccine is also necessary,” she said. “I think we’re now protected.”   

The Africa Centers for Disease Control and Prevention has estimated Congo needs at least 3 million mpox vaccines to stop the virus, and another 7 million for the rest of Africa. So far, WHO and partners have allocated 900,000 vaccines to nine African countries affected by mpox and expect 6 million vaccines to be available by the end of this year.  

Mpox epidemics in Burundi, Kenya, Rwanda and Uganda had their origins in Congo, and a number of cases in travelers have also been identified in Sweden, Thailand, Germany, India and Britain.  

Fewer than half of the people who are most at risk in Congo have been vaccinated, according to Heather Kerr, Congo director for the International Rescue Committee.  

“We only have a tiny amount of vaccines, and nothing for the kids,” she said.  

The vaccines for Congo are largely coming from donor countries like the U.S and through UNICEF, which mainly uses taxpayer money to buy the shots.  

“We’re getting a charitable approach where we only see very small donations of vaccines to Africa,” said Dr. Chris Beyrer, director of the Global Health Institute at Duke University. “What we need is a public health approach where we immunize populations at scale.”  

Drugmaker Bavarian Nordic, which makes the most widely used mpox vaccine, said it would sell shots destined for Africa at the lowest price possible.  

The advocacy group Public Citizen estimated UNICEF paid $65 per dose of the Jynneos mpox vaccine made by Bavarian Nordic, far higher than nearly all other vaccines used in public health programs. 

Dr. Salim Abdool Karim, an infectious diseases expert at South Africa’s University of KwaZulu-Natal, said mpox outbreaks typically peak and disappear quickly because of how the virus spreads. This time, however, he said there are two complicating factors: the virus’ transmission via sex and the continued spillover from infected animals.  

“We’re in new territory with mpox this time,” he added. “But we’re never going to solve this until we vaccinate most of our people.” 

Lahore air pollution hits historic high, forcing school closures 

KARACHI — Unprecedented air pollution levels in Pakistan’s second-largest city of Lahore prompted authorities to take emergency measures on Sunday, including issuing work-from-home mandates and closing primary schools.  

The city held the top spot on a real-time list of the world’s most polluted cities on Sunday after recording its highest ever pollution reading of 1900 near the Pakistan-India border on Saturday, based on data released by the provincial government and Swiss group IQAir.  

The government has shut primary schools for a week, advising parents to ensure children wear masks, said Senior Minister of Punjab Marriyum Aurangzeb during a press conference, as a thick blanket of smog enveloped the city.  

Citizens have been urged to stay indoors, keep doors and windows shut, and avoid unnecessary travel, she said, adding that hospitals had been given smog counters.  

To reduce vehicle pollution, 50% of office employees would work from home, said Aurangzeb.  

The government has also imposed a ban on three-wheelers known as rickshaws and halted construction in certain areas to reduce the pollution levels. Factories and construction sites failing to comply with these regulations could be shut down, she said.  

Aurangzeb described the situation as “unexpected” and attributed the deterioration in air quality to winds carrying pollution from neighboring India.   

“This cannot be solved without talks with India,” she said, adding the provincial government would initiate talks with its bigger neighbor through Pakistan’s foreign ministry.   

The smog crisis in Lahore, similar to the situation in India’s capital Delhi, tends to worsen during cooler months due to temperature inversion trapping pollution closer to the ground.  

Nevada lithium mine will crush rare plant habitat US said is critical to its survival, lawsuit says

RENO, Nevada — Conservationists and a Native American tribe are suing the U.S. to try to block a Nevada lithium mine they say will drive an endangered desert wildflower to extinction, disrupt groundwater flows and threaten cultural resources.

The Center for Biological Diversity promised the court battle a week ago when the U.S. Interior Department approved Ioneer Ltd.’s Rhyolite Ridge lithium-boron mine at the only place Tiehm’s buckwheat is known to exist in the world, near the California line halfway between Reno and Las Vegas.

It is the latest in a series of legal fights over projects President Joe Biden’s administration is pushing under his clean energy agenda intended to cut reliance on fossil fuels, in part by increasing the production of lithium to make electric vehicle batteries and solar panels.

The new lawsuit says the Interior Department’s approval of the mine marks a dramatic about-face by U.S. wildlife experts who warned nearly two years ago that Tiehm’s buckwheat was “in danger of extinction now” when they listed it as an endangered species in December 2022.

“One cannot save the planet from climate change while simultaneously destroying biodiversity,” said Fermina Stevens, director of the Western Shoshone Defense Project, which joined the center in the lawsuit filed Thursday in federal court in Reno.

“The use of minerals, whether for EVs or solar panels, does not justify this disregard for Indigenous cultural areas and keystone environmental laws,” said John Hadder, director of the Great Basin Resource Watch, another co-plaintiff.

Rita Henderson, spokesperson for Interior’s Bureau of Land Management in Reno, said Friday the agency had no immediate comment.

Ioneer Vice President Chad Yeftich said the Australia-based mining company intends to intervene on behalf of the U.S. and “vigorously defend” approval of the project, “which was based on its careful and thorough permitting process.”

“We are confident that the BLM will prevail,” Yeftich said. He added that he doesn’t expect the lawsuit will postpone plans to begin construction next year.

The lawsuit says the mine will harm sites sacred to the Western Shoshone people. That includes Cave Spring, a natural spring less than 1.6 kilometers away described as “a site of intergenerational transmission of cultural and spiritual knowledge.”

But it centers on alleged violations of the Endangered Species Act. It details the Fish and Wildlife Service’s departure from the dire picture it painted earlier of threats to the 15-centimeter-tall wildflower with cream or yellow blooms bordering the open-pit mine Ioneer plans to dig. 

The mine’s permit anticipates up to one-fifth of the nearly 3.6 square kilometers the agency designated as critical habitat surrounding the plants — home to various pollinators important to their survival — would be lost for decades, some permanently.

When proposing protection of the 368 hectares of critical habitat, the service said “this unit is essential to the conservation and recovery of Tiehm’s buckwheat.” The agency formalized the designation when it listed the plant in December 2022, dismissing the alternative of less-stringent threatened status.

“We find that a threatened species status is not appropriate because the threats are severe and imminent, and Tiehm’s buckwheat is in danger of extinction now, as opposed to likely to become endangered in the future,” the agency concluded.

The lawsuit also discloses for the first time that the plant’s population, numbering fewer than 30,000 in the government’s latest estimates, has suffered additional losses since August that were not considered in the U.S. Fish and Wildlife Service’s biological opinion.

The damage is similar to what the bureau concluded was caused by rodents eating the plants in a 2020 incident that reduced the population as much as 60%, the lawsuit says.

The Fish and Wildlife Service said in its August biological opinion that while the project “will result in the long-term disturbance (approximately 23 years) of 146 acres (59 hectares) of the plant community … and the permanent loss of 45 acres (18 hectares), we do not expect the adverse effects to appreciably diminish the value of critical habitat as a whole.” 

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Time to ‘fall back’ an hour as daylight saving time ends

The good news: You will get a glorious extra hour of sleep. The bad: It’ll be dark by late afternoon for the next few months in the United States.

Daylight saving time ends at 2 a.m. local time Sunday, which means you should set your clock back an hour before you go to bed. Standard time will last until March 9, when we will again “spring forward” with the return of daylight saving time. 

“Fall back” should be easier. But it still may take a while to adjust your sleep habits, not to mention the downsides of leaving work in the dark or trying to exercise while there’s still enough light. Some people with seasonal affective disorder, a type of depression usually linked to the shorter days and less sunlight of fall and winter, may struggle, too. 

Some health groups, including the American Medical Association and American Academy of Sleep Medicine, have said it’s time to do away with time switches and that sticking with standard time aligns better with the sun — and human biology. 

Two states — Arizona and Hawaii — don’t change and stay on standard time. 

Here’s what to know about the twice-yearly ritual. 

How the body reacts to light 

The brain has a master clock that is set by exposure to sunlight and darkness. This circadian rhythm is a roughly 24-hour cycle that determines when we become sleepy and when we’re more alert. The patterns change with age, one reason that early-to-rise youngsters evolve into hard-to-wake teens. 

Morning light resets the rhythm. By evening, levels of a hormone called melatonin begin to surge, triggering drowsiness. Too much light in the evening — that extra hour from daylight saving time — delays that surge and the cycle gets out of sync. 

How do time changes affect sleep? 

Even an hour change on the clock can throw off sleep schedules — because even though the clocks change, work and school start times stay the same. 

That’s a problem because so many people are already sleep deprived. About 1 in 3 U.S. adults sleep less than the recommended seven-plus hours nightly, and more than half of U.S. teens don’t get the recommended eight-plus hours on weeknights. 

How to prepare for the time change 

Some people try to prepare for a time change jolt by changing their bedtimes little by little in the days before the change. There are ways to ease the adjustment, including getting more sunshine to help reset your circadian rhythm for healthful sleep. 

Agreement signed at UN summit gives Indigenous groups voice

CALI, Colombia — After two weeks of negotiations, delegates on Saturday agreed at the United Nations conference on biodiversity to establish a subsidiary body that will include Indigenous peoples in future decisions on nature conservation, a development that builds on a growing movement to recognize the role of the descendants of some regions’ original inhabitants in protecting land and combating climate change. 

The delegates also agreed to oblige major corporations to share the financial benefits of research when using natural genetic resources. 

Indigenous delegations erupted into cheers and tears after the historic decision to create the subsidiary body was announced. It recognizes and protects the traditional knowledge systems of Indigenous peoples and local communities for the benefit of global and national biodiversity management, said Sushil Raj, Executive Director of the Rights and Communities Global Program at the Wildlife Conservation Society. 

“It strengthens representation, coordination, inclusive decision making, and creates a space for dialogue with parties to the COP,” Raj told The Associated Press, also known as the Conference of Parties. 

Negotiators had struggled to find common ground on some key issues in the final week but came to a consensus after talks went late into Friday. 

‘Historical debt’ 

The COP16 summit, hosted in Cali, Colombia, was a follow-up to the historic 2022 accord in Montreal, which included 23 measures to save Earth’s plant and animal life, including putting 30% of the planet and 30% of degraded ecosystems under protection by 2030. 

A measure to recognize the importance of the role of people of African descent in the protection of nature was also adopted in Cali. 

The Indigenous body will be formed by two co-chairs elected by COP: one nominated by U.N. parties of the regional group, and the other nominated by representatives of Indigenous peoples and local communities, the AP saw in the final document. 

At least one of the co-chairs will be selected from a developing country, taking into account gender balance, the document said. 

“With this decision, the value of the traditional knowledge of indigenous peoples, Afro-descendants and local communities is recognized, and a 26-year-old historical debt in the Convention on Biological Diversity [CBD] is settled,” Susana Muhamad, Colombia’s environment minister and COP16 president, posted on social media platform X shortly after the announcement. 

Who owns nature’s DNA was one of the most contentious and fiercely negotiated topics at the summit as tensions spiked between poorer and developed countries over digital sequence information on genetic resources, or DSI. 

Negotiators consented on Saturday morning, however, to bind big companies to share benefits when using resources from animals, plants or microorganisms in biotechnologies. 

Delegations agreed on a genetic information fee of 0.1% of companies’ revenues from products derived from such information. 

“Many of the life-saving medicines we use today come from the rainforest. It is therefore right that a portion of the income companies generate from this information goes back to protect nature,” said Toerris Jaeger, executive director of Rainforest Foundation Norway. “This is the absolute highlight from COP16.” 

Needs exceed pledges

Also adopted was an agreement to protect human health from Earth’s increasing biodiversity issues. Ecosystem degradation and loss of ecological integrity directly threaten human and animal health, environmental groups say. 

Pledges made by countries during the two weeks were far short of the billions needed to tackle plummeting global biodiversity, with only around $400 million in the fund. 

The modest pledges don’t bode well for the next U.N. climate talks, COP29, to take place in Azerbaijan beginning later this month. COP29 is expected to focus on how to generate trillions of dollars needed for the world to transition to clean energies such as solar, wind and geothermal. Raising that money will require major commitments by nations, companies and philanthropies. 

In Montreal’s biodiversity summit, wealthy nations pledged to raise $20 billion in annual conservation financing for developing nations by 2025, with that number rising to $30 billion annually by 2030. 

Global wildlife populations have plunged on average by 73% in 50 years, according to the World Wildlife Fund and the Zoological Society of London biennial Living Planet report in October. 

California attempts to regulate election deepfakes

The state of California has passed several laws attempting to regulate artificial intelligence, including AI used to create realistic looking but manipulated audio or video — known as a deepfake. In this U.S. election season, the aim is to counter misinformation. But it has raised concerns about free speech. From California, Genia Dulot has our story.

Robot retrieves first melted fuel from Fukushima nuclear reactor

TOKYO — A remote-controlled robot has safely returned with a tiny piece of melted fuel it collected from inside one of three damaged reactors at the tsunami-hit Fukushima Daiichi nuclear power plant for the first time since the 2011 meltdown.

Tokyo Electric Power Company Holdings, which manages the plant, said Saturday that the extendable fishing rod-like robot successfully clipped a gravel as big as 5 millimeters, the size of a tiny granola bit, from the top surface of a mound of molten fuel debris that sits on the bottom of the No. 2 reactor’s primary containment vessel.

The Telesco robot, with its frontal tongs still holding the melted fuel bit, returned to the enclosed container for safe storage after workers in full hazmat gear pulled it out of the containment vessel earlier Saturday.

The sample marks the first time that melted fuel has been retrieved out of the containment vessel. But the mission is not over until it’s certain that the sample’s radioactivity is below a set standard and safely placed into a container.

If the radioactivity exceeds the limit, the robot must go back inside the reactor to find another piece. TEPCO officials said they expect the piece is small enough to meet the requirement.

The mission initially started in August for what was supposed to be a two-week round trip but had been suspended twice due to mishaps.

The first one was the procedural mistake at the beginning that held up the work for nearly three weeks. Then the robot’s two cameras, designed to transmit views of the target areas for its operators in the remote-control room, failed. The camera problem required the robot to be pulled out all the way for replacement before the mission resumed Monday.

Fukushima Daiichi lost its key cooling systems during the 2011 earthquake and tsunami, causing meltdowns in its three reactors. An estimated 880 tons of fatally radioactive molten fuel remains in them, and TEPCO has carried out a number of robotic probes to figure out how to decommission the plant.

Telesco on Wednesday successfully clipped a piece presumably measuring less than 3 grams (0.1 ounce) from the planned area right underneath the Unit 2 reactor core, from which large amounts of melted fuel fell during the meltdown 13 years ago, TEPCO said.

Plant chief Akira Ono said only the tiny spec can provide key data to plan decommissioning strategy, develop necessary technology and robots and retroactively learn how the accident developed.

The government and TEPCO have set a 30-to-40-year target for the cleanup, which experts say is overly optimistic and should be updated.

No specific plan for the full removal of the fuel debris or its final disposal has been decided.