washington — The NASA astronaut knocks loudly three times on what appears to be a nondescript door and calls cheerfully: “You ready to come out?” 

The reply is inaudible, but beneath his mask he appears to be grinning as he yanks the door open, and four scientists who have spent a year away from all other human contact, simulating a mission to Mars, spill out to cheers and applause. 

Anca Selariu, Ross Brockwell, Nathan Jones and team leader Kelly Haston have spent the past 378 days sealed inside the “Martian” habitat in Houston, Texas, part of NASA’s research into what it will take to put humans on the Red Planet.  

They have been growing vegetables, conducting “Marswalks,” and operating under what NASA terms “additional stressors,” such as communication delays with “Earth,” including their families; isolation and confinement.  

It’s the kind of experience that would make anyone who lived through pandemic lockdowns shudder, but all four were beaming as they reemerged Saturday, their hair slightly more unruly and their emotion apparent.  

“Hello. It’s actually so wonderful just to be able to say hello to you,” Haston, a biologist, said with a laugh. 

“I really hope I don’t cry standing up here in front of all of you,” Jones, an emergency room doctor, said as he took to the microphone, and nearly doing just that several moments later as he spotted his wife in the crowd.  

The habitat, dubbed Mars Dune Alpha, is a 3D-printed, 160-square-meter facility, complete with bedrooms, a gym, common areas, and a vertical farm for growing food. 

An outdoor area, separated by an airlock, is filled with red sand and is where the team donned suits to conduct their “Marswalks,” though it is still covered rather than being open air. 

“They have spent more than a year in this habitat conducting crucial science, most of it nutrition-based and how that impacts their performance … as we prepare to send people on to the Red Planet,” Steve Koerner told the crowd. Koerner is the deputy director at NASA’s Johnson Space Center. 

“I’m very appreciative,” he added. 

This mission is the first of a series of three planned by NASA, grouped under the title CHAPEA — Crew Health and Performance Exploration Analog. 

A yearlong mission simulating life on Mars took place in 2015-2016 in a habitat in Hawaii, and although NASA participated in it, it was not at the helm. 

Under its Artemis program, America plans to send humans back to the Moon to learn how to live there long-term to help prepare a trip to Mars, sometime towards the end of the 2030s. 
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portland, oregon — Roughly 130 million people were under threat Saturday and into next week from a long-running heat wave that already has broken records with dangerously high temperatures — and is expected to shatter more from East Coast to West Coast, forecasters said.

Oppressive heat and humidity could team up to spike temperatures above 100 degrees Fahrenheit (about 38 degrees Celsius) in parts of the Pacific Northwest, the Mid-Atlantic and the Northeast, said Jacob Asherman, a meteorologist with the National Weather Service.

In Oregon, records could be broken in cities including Eugene, Portland and Salem, Asherman said. Dozens of other records throughout the U.S. could fall, Asherman added, causing millions to seek relief from the blanket of heat in cooling centers from Bullhead City, Arizona, to Norfolk, Virginia.

The National Weather Service said Saturday it was extending the excessive heat warning for much of the Southwest into Friday.

“A dangerous and historic heatwave is just getting started across the area, with temperatures expected to peak during the Sunday-Wednesday timeframe,” the National Weather Service in Las Vegas, Nevada, said in an updated forecast.

Excessive heat will likely continue through Friday, the service said.

In sweltering Las Vegas, where the temperature hit 100 F (37.7 C) by 10:30 a.m., Marko Boscovich said the best way to beat the heat is in a seat at a slot machine with a cold beer inside an air-conditioned casino.

“But you know, after it hits triple digits it’s about all the same to me,” said Boscovich, who was visiting from Sparks, Nevada, to see a Dead & Company concert later Saturday night at the Sphere. “Maybe they’ll play one of my favorites — ‘Cold Rain and Snow.'”

Heat records shatter

By 10:30 a.m. Saturday, the National Weather Service said the temperature already had risen to 100 F (36.6 C) in Phoenix, which saw a record high of 118 F (47.7 C) for Friday.

Meteorologists predict temperatures will be near daily records region-wide through most, if not all, of the coming week with lower desert highs reaching 115 to 120 F (46.1 to 48.8 C).

Rare heat advisories had been extended even into the upper elevations, including around Lake Tahoe on the California-Nevada border. The National Weather Service in Reno, Nevada, warned of “major heat risk impacts, even in the mountains.”

“How hot are we talking? Well, high temperatures across (western Nevada and northeastern California) won’t get below 100 degrees (37.8 C) until next weekend,” the service posted online. “And unfortunately, there won’t be much relief overnight either.”

A new heat record for the day was set Friday in California’s Death Valley — one of the hottest places on Earth — with the mercury climbing to 127 F (52.8 C). The old mark of 122 F (50 C) was last tied in 2013.

Palm Springs, California, hit 124 F (51.1 C) Friday, breaking the city’s record of 123 F (50.5 C).

More extreme highs are in the near forecast, including 129 F (53.8 degrees C) for Sunday at Furnace Creek in Death Valley National Park, and then around 130 (54.4 C) through Wednesday. The hottest temperature ever officially recorded on Earth was 134 degrees (56.67 C) in Death Valley in July 1913, though some experts dispute that measurement and say the real record was 130 F (54.4 C) recorded there in July 2021.

Worst yet to come

The worst was yet to come across much of the West, with triple-digit temperatures likely higher than average into next week, the National Weather Service said.

The Eastern U.S. also was bracing for more hot temperatures. Baltimore and other parts of Maryland were under an excessive heat warning, as heat index values could climb to 110 F (43 C), forecasters said.

Heat leads to some deaths

In Arizona’s Maricopa County, which encompasses Phoenix, there have been at least 13 confirmed heat-related deaths this year, along with more than 160 other suspected heat deaths are still under investigation, according to the county’s most recent report.

That does not include the death of a 10-year-old boy this week in Phoenix who suffered a “heat-related medical event” while hiking with family at South Mountain Park and Preserve, according to police.
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Lausanne, Switzerland — In the battle against drug use at the Paris Olympics, the International Testing Agency plans to deploy a more streamlined, high-tech approach to identify and target potential cheats.

In an interview with Agence France-Presse, Benjamin Cohen, director general of the ITA, said potential tools at its disposal included biological and performance passports as well as a mountain of other data.

Upgraded software, possibly using artificial intelligence, could also help; an investigative unit aided by whistleblowers was making inroads; and increased cooperation with sports bodies and police was bearing fruit.

The ITA, which was founded in 2018, runs the anti-doping program for the Olympics, the Tour de France and “more than 65 international organizations,” said Cohen.

The challenge was to refine the “risk analysis” and identify athletes to monitor using as little time and resources as possible, said Cohen, a Swiss lawyer who has headed the agency since its creation.

The problem is accentuated in the run-up to the Paris Games.

“We still have 30,000 potentially qualifying athletes and we cannot wait to have the final list to focus on the 11,000 participants,” Cohen said.

“Certain doping practices enable athletes to achieve results very quickly,” he said. “Traditionally the pre-Olympic period is high-risk time … the last moment to make a difference. Athletes know that they will be very closely monitored at the Olympics, so I would hope that very few, if any, will be tempted to take drugs in the Olympic Village in Paris.”

At the Games, only medalists are automatically tested, but the ITA wants to find ways to target potential dopers before the finish.

Cohen said the ITA tries to identify patterns. It looks at the demands of each discipline and the substances it might tempt athletes to use. Then the ITA looks at delegations and “the history of doping in that country.” Finally, it scrutinizes each individual athlete and “the development of his or her performances, any suspicious biological passport profiles, suspicious anti-doping tests and so on.”

“That’s hundreds of thousands of pieces of data.”

“Risk analysis”

“Today we have our own software, and the next stage” will involve “programming computers to extract this data, because we still do a lot of this work manually.”

After that, the ITA hopes to “seize all the opportunities offered by artificial intelligence,” provided “we use these new tools ethically.”

“If it’s done properly,” he said, “AI will enable us to go much further in risk analysis and prediction.”

The ITA is developing a “performance passport” as a counterpart to the long-established biological passport.

The objective is to “predict results on the basis of what an athlete has done over the last four years,” said Cohen.

“Artificial intelligence will enable us to say: ‘This is really an unusual result, which could suggest doping,'” he said. “It could help us flag them.”

The performance passport project was initially tested in swimming and weightlifting, two indoor sports in which athletes compete in identical environments each time.

Weightlifting also is one of the sports that have returned a vast number of positive tests at Summer Olympics.

In 2021, the ITA carried out “a major investigation into weightlifting,” and that enabled them to set up a specialized unit in cooperation with the sport.

Focus on cycling

It now has more than 10 such units. “Cycling is a particular focus,” but “other sports are beginning to understand the benefits of gathering intelligence, having anonymous sources and promoting whistleblowers.”

“It’s a new method that complements traditional testing.”

Cohen said the ITA has been working to build links with law enforcement and exploit “synergies.”

“They are bearing fruit,” he said, referring to the case of 23-year-old Italian cyclist Andrea Piccolo, arrested on June 21 by the Italian Carabinieri who caught him returning to the country with growth hormones.

“ITA asked the Italian authorities to open his luggage, which would not have been possible six years ago,” Cohen said.

“We carry out the controls, we monitor the performances of these athletes, we know the networks, the doctors involved and the drugs they are taking. And they can seize and open suitcases and enter hotel rooms.”
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new york — The extent of Hurricane Beryl’s damage became clearer Friday, as communications were reestablished with the small, storm-ravaged eastern Caribbean islands and relief began to arrive. 

The Grenadian islands of Carriacou and Petit Martinique sustained the most severe damage when Beryl made landfall Monday as a Category 4 storm and later saw its winds strengthen to a Category 5. About 11,000 people inhabit the two islands. 

“The desalination plants have been knocked out; all of the cell towers have been knocked out; all of the fiber optic cables have been knocked out,” said Simon Springett, the United Nations resident coordinator for Barbados and the Eastern Caribbean. “The roads are impassable. We probably have about 95% of the housing stock destroyed. And by default, all of the local businesses, all the income-generating activities — and the list goes on.” 

Beryl is the first Category 5 hurricane on record in the Atlantic Ocean in June. The hurricane season runs until November 30 and officials with the National Oceanic and Atmospheric Administration are forecasting 17 to 25 named storms.

Springett, who briefed reporters from Grenada, said communications were only restored with Carriacou Thursday night. About 9,000 people live on the island known for its coral reefs and sandy beaches. 

“The entire island is completely affected,” he said. 

Rough seas hamper delivery of help

Springett said the relief operation has been complicated by extremely rough seas following the hurricane and airport control towers being knocked offline. 

“So, there is only fly-by visibility,” he said. “Even when things get into the airport, there are no roads to be able to access the goods.” 

He said a French naval vessel is due to arrive in Carriacou on Friday. Neighbors Guyana and Trinidad and Tobago also have sent support. 

The United Nations, which has nine agencies active in Grenada normally, is surging more staff in. Springett said a supply ship would be arriving Saturday from St. Vincent and the Grenadines to bring aid to the outer islands of the Grenadines and then continue to Carriacou and Petite Martinique. 

Three islands in St. Vincent and the Grenadines also were hit badly: Canouan, Union Island and Mayreau. Springett said about 15,500 people live there. 

One confirmed death in Jamaica

Beryl hit Jamaica Wednesday. It was the strongest storm there in over a decade, but the island was spared the worst. 

Dennis Zulu, U.N. resident coordinator for Jamaica, told reporters on the same briefing call that about 70% of people are without water and 40% without power. 

The island is a major tourism destination and Zulu said the government had moved quickly to reopen the main tourist airport at Montego Bay and to clear road access to resorts. 

“From preliminary assessments, very little harm came to the infrastructure in terms of tourist hotels and resorts,” Zulu said.  “So that is really positive.” 

He said at least one person was confirmed dead in Jamaica from Beryl and a flash flood warning remains in effect. There was damage to homes, but some government shelters were shutting after people had returned home. 

“Jamaica is up and running, if I may say that, and the government is moving seriously to ensure that,” Zulu said. 

The United Nations has made an initial allocation of $1.5 million from its emergency fund for Grenada and St. Vincent and the Grenadines. Another $2.5 million has been allocated for Jamaica. 
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Violence against reporters covering environmental issues is trending upward, according to UNESCO and media advocates. For VOA News, Robin Guess reports.
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July 20 marks the 55th anniversary of the Apollo 11 landing on the moon. An interactive exhibit at Manhattan’s Intrepid Museum reminds viewers of the enormity of that undertaking and what went into the first moon landing. Evgeny Maslov has the story, narrated by Anna Rice. Videographer: Vladimir Badikov.
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BENGALURU, India — Months of scorching temperatures sometimes over 50 degrees Celsius (122 Fahrenheit) in parts of India this year — its worst heat wave in over a decade — left hundreds dead or ill. But the official number of deaths listed in government reports barely scratches the surface of the true toll and that’s affecting future preparations for similar swelters, according to public health experts. 

India now has a bit of respite from the intense heat, and a different set of extreme weather problems as monsoon rain lashes the northeast, but for months the extreme heat took a toll on large swaths of the country, particularly in northern India, where government officials reported at least 110 heat-related deaths. 

Public health experts say the true number of heat-related deaths is likely in the thousands but because heat is often not listed as a reason on a death certificate many heat deaths don’t get counted in official figures. The worry, they say, is that undercounting the deaths means the heat wave problem isn’t as prioritized as it should be, and officials are missing out on ways to prepare their residents for the scorching temperatures. 

All of India’s warmest years on record have been in the last decade. Studies by public health experts found that up to 1,116 people have died every year between 2008 and 2019 due to heat. 

Difficulties registering heat deaths 

As part of his work in public health, Srinath Reddy, the founder of the Public Health Foundation of India, has advised state governments on how to factor in heat when recording deaths. 

He found that as a result of “incomplete reporting, delayed reporting and misclassification of deaths,” heat-related deaths are significantly undercounted around the country. Despite national guidelines for recording deaths, many doctors — especially those in overcrowded public hospitals where resources are already strained — don’t follow it, he said. 

“Most doctors just record the immediate cause of death and attribution to environmental triggers like heat are not recorded,” Reddy said. That’s because heat deaths can be classified as exertional or non-exertional: Exertional is when a person dies due to direct exposure to high temperatures and non-exertional is when young children, older people or people with pre-existing health conditions become seriously ill or sometimes die from the heat, even if indoors. 

“The heatwave is the final straw for the second category of people,” said Dileep Mavalankar, former head of the Indian Institute of Public Health in Gandhinagar. “Most people dying during heat waves belong to this category but their deaths are not recorded as connected to the heat.” 

Mavalankar agreed the official number of heat deaths this year is an undercount. He said there were 40,000 recorded case of heat stroke, but only 110 deaths. “This is just 0.3% of the total number of heatstroke cases recorded, but usually heat deaths should be 20 to 30% of heatstroke cases,” he said. 

“We need to be counting deaths better,” Mavalankar said. “That is the only way we will know how severe the consequences of extreme heat are.” 
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Russian shelling continues to degrade Ukraine’s energy system. Some parts of the country now have access to electricity for just a few hours a day. New generators aim to help supply residents with power and hot water. Tetiana Kukurika has the story, narrated by Anna Rice.
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Tokyo — Japan’s top court ruled on Wednesday that a defunct eugenics law under which thousands of people were forcibly sterilized between 1948 and 1996 was unconstitutional.

The Supreme Court also declared that a 20-year statute of limitations could not be applied, paving the way for compensation claims from victims after years of legal battles.

“For the state to evade responsibility for damages payments would be extremely unfair and unjust, and absolutely intolerable,” the court in Tokyo said.

Japan’s government acknowledges that around 16,500 people were forcibly sterilized under the law that aimed to “prevent the generation of poor quality descendants.”

An additional 8,500 people were sterilized with their consent, although lawyers say even those cases were likely “de facto forced” because of the pressure individuals faced.

A 1953 government notice said physical restraint, anesthesia and even “deception” could be used for the operations.

“There are people who couldn’t be here today. There are those who died as well. I want to visit the grave of my parents and tell them we’ve won,” victim Saburo Kita, who uses a pseudonym, told reporters after the ruling.

Kita was convinced to undergo a vasectomy when he was 14 at a facility housing troubled children. He only told his wife what had happened shortly before she died in 2013.

“But a complete resolution of this issue hasn’t been realized yet. Together with lawyers, I will continue to fight,” said Kita, one of several victims who celebrated outside the court, some in wheelchairs.

Apology

The number of operations in Japan slowed to a trickle in the 1980s and 1990s before the law was scrapped in 1996.

That dark history was thrust back under the spotlight in 2018 when a woman in her 60s sued the government over a procedure she had undergone at age 15, opening the floodgates for similar lawsuits.

The government, for its part, “wholeheartedly” apologized after legislation was passed in 2019 stipulating a lump-sum payment of 3.2 million yen (around $20,000 today) per victim.

However, survivors say that was too little to match the severity of their suffering and took their fight to court.

Regional courts have mostly agreed in recent years that the eugenics law was a violation of Japan’s constitution.

However, judges have been divided on whether claims are valid beyond the 20-year statute of limitations.

Some ordered the state to pay damages but others dismissed cases, saying the window for pursuing damages had closed.

Prime Minister Fumio Kishida said the government would “swiftly pay damages based on the finalized ruling” and discuss “the new ways in which (victims) can be compensated.”

The government “sincerely apologizes” for the policy that “trampled on the human dignity” of victims, Kishida said, adding he would meet survivors in coming weeks to listen “face-to-face to their stories of suffering.”

A group of victims said on Wednesday it “wholeheartedly” welcomed the ruling.

“We cannot forgive the irresponsibility of the government and its lack of human rights awareness, as well as the fact that what is now described as the biggest human rights violation in Japan’s post-war history was left unaddressed for such a long time,” the group said in a statement.

Lawyer Koji Niizato said it was “the best ruling we could have hoped for.”

“Victims of the eugenics law put up a wonderful fight, one that influenced the Supreme Court and changed society,” Niizato said.
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As the Caribbean sees its first Category 5 hurricane of the year, scientists warn that extreme weather is here to stay due to climate change. Aru Pande reports from Washington, where U.S. President Joe Biden on Tuesday announced new climate resilience measures. Kim Lewis contributed to this report.
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WASHINGTON — U.S. officials have approved another Alzheimer’s drug that can modestly slow the disease, providing a new option for patients in the early stages of the incurable, memory-destroying ailment. 

The Food and Drug Administration approved Eli Lilly’s Kisunla on Tuesday for mild or early cases of dementia caused by Alzheimer’s. It’s only the second drug that’s been convincingly shown to delay cognitive decline in patients, following last year’s approval of a similar drug from Japanese drugmaker Eisai. 

The delay seen with both drugs amounts to a matter of months — about seven months, in the case of Lilly’s drug. Patients and their families will have to weigh that benefit against the downsides, including regular IV infusions and potentially dangerous side effects like brain swelling. 

Physicians who treat Alzheimer’s say the approval is an important step after decades of failed experimental treatments. 

“I’m thrilled to have different options to help my patients,” said Dr. Suzanne Schindler, a neurologist at Washington University in St. Louis. “It’s been difficult as a dementia specialist — I diagnose my patients with Alzheimer’s and then every year I see them get worse and they progress until they die.” 

Both Kisunla and the Japanese drug, Leqembi, are laboratory-made antibodies, administered by IV, that target one contributor to Alzheimer’s: sticky amyloid plaque buildup in the brain. Questions remain about which patients should get the drugs and how long they might benefit. 

The new drug’s approval was expected after an outside panel of FDA advisers unanimously voted in favor of its benefits at a public meeting last month. That endorsement came despite several questions from FDA reviewers about how Lilly studied the drug, including allowing patients to discontinue treatment after their plaque reached very low levels. 

Costs will vary by patient, based on how long they take the drug, Lilly said. The company also said a year’s worth of therapy would cost $32,000 — more than the $26,500 price of a year’s worth of Leqembi. 

The FDA’s prescribing information tells doctors they can consider stopping the drug after confirming via brain scans that patients have minimal plaque. 

More than 6 million Americans have Alzheimer’s. Only those with early or mild disease will be eligible for the new drug, and an even smaller subset are likely to undergo the multistep process needed to get a prescription. 

The FDA approved Kisunla, known chemically as donanemab, based on results from an 18-month study in which patients given the treatment declined about 22% more slowly in terms of memory and cognitive ability than those who received a dummy infusion. 

The main safety issue was brain swelling and bleeding, a problem common to all plaque-targeting drugs. The rates reported in Lilly’s study, including 20% of patients with microbleeds, were slightly higher than those reported with competitor Leqembi. However, the two drugs were tested in slightly different types of patients, which experts say makes it difficult to compare the drugs’ safety. 

Kisunla is infused once a month compared to Leqembi’s twice-a-month regimen, which could make things easier for caregivers who bring their loved ones to a hospital or clinic for treatment.
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islamabad — A new study has revealed that recent floods in Pakistan have substantially weakened its societal resilience in coping with and recovering from such disasters as the threat from climate change continues to grow.

The London-headquartered independent global charity Lloyd’s Register Foundation said Tuesday the findings are part of the latest edition of their flagship World Risk Poll Resilience Index.

The study also highlighted that the number of Pakistanis who have experienced a disaster in the past five years has more than doubled since 2021, increasing from 11% to 27%.

“This increase has been driven primarily by the extensive floods that hit the country in 2022, affecting regions containing around 15% of the population,” the study said.

The report noted that community and society resilience scores declined sharply in the regions most affected by the floods, particularly in the southern Sindh province.

“These scores declined because people reported losing confidence in the support of the government, community and infrastructure — at a national level, those who said their government cared ‘not at all’ about them and their well-being rose from 60% in 2021 to almost three-quarters [72%] in 2023.”

Meanwhile, the country’s already low individual and household resilience levels failed to improve, with Pakistan ranking in the bottom 10 globally for both resilience scores, according to the report.

Nancy Hey, the director of evidence and insight at Lloyd’s Register Foundation, urged policymakers in Pakistan to prioritize rebuilding and strengthening the resilience of the most affected communities.

She said this would better prepare them to face natural hazards and other potential causes of disasters in the wake of the growing threat of climate change.

“For residents of Pakistan, catastrophic flooding is largely responsible for the doubling in disaster experience since 2021. This may have led to a ‘reality check’ for residents in terms of how prepared they feel for such events, with community and societal resilience particularly negatively affected,” Hey said.

In 2022, Pakistan’s southern and southwestern regions experienced devastating floods triggered by climate change-induced unusually heavy monsoon rains, killing more than 1,700 people, affecting 33 million others, and submerging approximately one-third of Pakistan.

The South Asian nation of about 245 million contributes less than 1% to global carbon emissions but bears the brunt of climate change.

The country’s weather patterns have changed dramatically in recent years, and it officially “ranks fifth among the countries most affected by global warming.”

April was recorded as the wettest month in Pakistan since 1961, with more than double the usual monthly rainfall, killing scores of people and destroying property as well as farmland.

In May and June, Pakistan experienced relatively hotter heat waves, with temperatures in some districts rising to more than 52 degrees Celsius for days. The hot weather prompted authorities in May to temporarily shut down education for half of Pakistan’s schoolchildren to protect them from heatstroke and dehydration.

The United Nations has warned that an estimated 200,000 Pakistanis could be affected by the coming monsoon season and flash floods, as national weather forecasters project above-normal rainfall.

Prime Minister Shehbaz Sharif reviewed preparations for the monsoon season at a special meeting Tuesday and formed “a high-level committee” to handle potential emergencies, his office said in a statement.

National Disaster Management Authority officials told the meeting that all relevant institutions and Pakistani troops remain on “high alert” in vulnerable districts. They were quoted as saying that “adequate stocks” of boats, tents, drainage pumps, medicines and other essential items were available for people in areas prone to rain-related disasters.”
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